注意！孩子身上的这种胎记，可能隐藏疾病风险

本资料由阿斯利康提供，仅供公众人士医学科普使用，不用于任何临床指导或推广目的。

如有任何疾病或诊疗相关问题，请咨询临床医生。

审批号：CN-137907；有效期至：2025-02-10

参考文献

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[2] Almuhaidib S R, Aldulijan F A, Alkanaan N A, et. al. An approach to café au lait macules in primary care setting[J]. J Family Community Med, 2021 Sep-Dec;28(3):217-219.

[3] 中国罕见病联盟Ⅰ型神经纤维瘤病多学科诊疗协作组. Ⅰ型神经纤维瘤病多学科诊治指南(2023版)[J]. 罕见病研究, 2023, 2(2): 210-230

[4] 王智超,李青峰.Ⅰ型神经纤维瘤病临床诊疗专家共识（2021版）[J].中国修复重建外科杂志,2021,35(11):1384-1395.

[5] Shay, Ben-Shachar,Tom, Dubov,Hagit, Toledano-Alhadef et al. Predicting neurofibromatosis type 1 risk among children with isolated café-au-lait macules.[J] .J Am Acad Dermatol, 2017, 76: 0.

[6] Rasmussen SA, Yang Q, Friedman JM. Mortality in neurofibromatosis 1: an analysis using U.S. death certificates. Am J Hum Genet. 2001 May;68(5):1110-8. doi: 10.1086/320121. Epub 2001 Mar 28. PMID: 11283797; PMCID: PMC1226092.