饶议科学

星期一小夜曲:化学生物学

1. Kwon H, Bers AE, Barbie DA.(2026).Degrading TBK1 to disarm VHL-deficient renal cancer.Cell Chemical Biology 33: 425-427.

2. Li B, Li Y, Zhang J, et al.(2026).Lysosome-targeting chimeras enable targeted protein degradation.Cell Chemical Biology 33: 433-460.

3. Liao C, Lyu S, Johnson RL, et al. (2026). Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression. Cell Chemical Biology33:461-473.

4. Gustafsen C, Vilstrup J, Kristensen M, et al. (2026).Reshaping the progranulin/sortilin interaction for targeted degradation of extracellular proteins.Cell Chemical Biology 33:490-505.

5. Tong B, Wang Y, Wei J, et al. (2026). A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway.Cell Chemical Biology 33:523-537.

6. Ma X, Vaillant F, Gopal D, et al. (2026). IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes.Cell Chemical Biology 33:553-570.

7. Tong J, Watkins J, Burke J, et al. (2026).Assessing the suitability of deubiquitylases as substrates for targeted protein degradation.Cell Chemical Biology33:571-581.